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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PKD2L1 Polyclonal Antibody

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货号 TMAB-11498

Anti-PKD2L1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PKD2L1。Anti-PKD2L1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-PKD2L1 Polyclonal Antibody

Anti-PKD2L1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-11498

Anti-PKD2L1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PKD2L1。Anti-PKD2L1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-PKD2L1 Polyclonal Antibody is a Rabbit antibody targeting PKD2L1. Anti-PKD2L1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell projection › cilium membrane; Multi-pass membrane protein
组织特异性Expressed in adult heart, skeletal muscle, brain, spleen, testis, retina and liver. According to PubMed:9748274, expressed at high levels in fetal tissues, including kidney and liver, and down-regulated in adult tissues. According to PubMed:10602361, expressed in fetal brain, but not expressed in fetal lung, liver or kidney. Isoform 4 appears to be expressed only in transformed lymphoblasts.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. This protein functions as a calcium-regulated nonselective cation channel. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
抗原信息
免疫原
KLH conjugated synthetic peptide: human PKD2L1
抗原种属
Human
基因名称
PKD2L1
基因ID
9033
蛋白名称
Polycystic kidney disease 2-like 1 protein
Uniprot ID
Q9P0L9
功能
Pore-forming subunit of a ciliary calcium channel that controls calcium concentration within primary cilia without affecting cytoplasmic calcium concentration. Forms a heterodimer with PKD1L1 in primary cilia and forms a calcium-permeant ciliary channel that regulates sonic hedgehog/SHH signaling and GLI2 transcription. May act as a sour taste receptor by forming a calcium channel with PKD1L3 in gustatory cells; however, its contribution to sour taste perception is unclear in vivo and may be indirect.
化学信息
分子量Theoretical: 92 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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