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Anti-PIP5KL1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PIP5KL1。Anti-PIP5KL1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-PIP5KL1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PIP5KL1。Anti-PIP5KL1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-PIP5KL1 Polyclonal Antibody is a Rabbit antibody targeting PIP5KL1. Anti-PIP5KL1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 反应种属 | Mouse,Rat (predicted:Human,Dog,Cow,Horse,Rabbit) |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Membrane. Note=Localized to large cytoplasmic vesicular structures. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | PIPKH, also known as PIP5KL1 (phosphatidylinositol-4-phosphate 5-kinase-like 1), is a 394 amino acid phosphoinositide kinase-like protein that contains one PIPK domain. Although PIPKH lacks intrinsic lipid kinase activity, it associates with type I PIPKs and may play a role in localization of PIPK activity. Encoded by a gene that maps to human chromosome 9q34.11, PIPKH localizes to cytoplasm, specifically to large cytoplasmic vesicular structures, and exists as two alternatively spliced isoforms. Highly expressed in brain and testis, PIPKH is also expressed at very low levels in heart, spleen, lung, liver, skeletal muscle and kidney. PIPKH heterodimerizes with other type I phosphatidylinositol-4-phosphate 5-kinases, and may function as a scaffold to localize and regulate kinases to specific cell compartments. Overexpression of PIPKH may suppress cell proliferation and migration in human gastric cancer cells and may also inhibit cervical cancer formation. |
| 免疫原 | KLH conjugated synthetic peptide: human PIP5KL1 |
| 抗原种属 | Human |
| 基因名称 | PIP5KL1 |
| 基因ID | |
| 蛋白名称 | Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 |
| Uniprot ID | |
| 功能 | May act as a scaffold to localize and regulate type I PI(4)P 5-kinases to specific compartments within the cell, where they generate PI(4,5)P2 for actin nucleation, signaling and scaffold protein recruitment and conversion to PI(3,4,5)P3. |
| 分子量 | Theoretical: 45 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |