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Anti-PIK3R5 Polyclonal Antibody

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货号 TMAB-11454

Anti-PIK3R5 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PIK3R5。Anti-PIK3R5 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-PIK3R5 Polyclonal Antibody

Anti-PIK3R5 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-11454

Anti-PIK3R5 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PIK3R5。Anti-PIK3R5 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-PIK3R5 Polyclonal Antibody is a Rabbit antibody targeting PIK3R5. Anti-PIK3R5 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Pig,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Membrane; Peripheral membrane protein.
组织特异性Ubiquitously expressed with high expression in fetal brain compared to adult brain. Abundant expression is observed in cerebellum, cerebral cortex, cerebral meninges, and vermis cerebelli.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found. [provided by RefSeq, Oct 2011]
抗原信息
免疫原
KLH conjugated synthetic peptide: human PIK3R5
抗原种属
Human
基因名称
PIK3R5
基因ID
蛋白名称
phosphoinositide 3-kinase regulatory subunit 5
Uniprot ID
功能
Regulatory subunit of the PI3K gamma complex. Required for recruitment of the catalytic subunit to the plasma membrane via interaction with beta-gamma G protein dimers. Required for G protein-mediated activation of PIK3CG.
化学信息
分子量Theoretical: 97 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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