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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-PIK3CA Monoclonal Antibody (7T396)

Synonyms: PI3K, p110-alpha
货号 TMAT-1030 一键复制产品信息
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Anti-PIK3CA Monoclonal Antibody (7T396) 是一种 Mouse 抗体，靶向 PIK3CA。Anti-PIK3CA Monoclonal Antibody (7T396) 可用于 IHC,IF,FCM。

Anti-PIK3CA Monoclonal Antibody (7T396)

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Rating icon 还可以
货号 TMAT-1030

别名 PI3K, p110-alpha

Anti-PIK3CA Monoclonal Antibody (7T396) 是一种 Mouse 抗体，靶向 PIK3CA。Anti-PIK3CA Monoclonal Antibody (7T396) 可用于 IHC,IF,FCM。

Anti-PIK3CA Monoclonal Antibody (7T396)
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产品介绍

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产品描述
Anti-PIK3CA Monoclonal Antibody (7T396) is a Mouse antibody targeting PIK3CA. Anti-PIK3CA Monoclonal Antibody (7T396) can be used in IHC,IF,FCM.
别名
PI3K, p110-alpha
Ig Type
IgG2a
克隆号
7T396
反应种属
Human,Mouse,Rat,Rabbit
应用IHCIFFCM
推荐剂量
IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide.
浓度1 mg/mL
研究背景PIK3CA is the most mutated gene in breast cancer and is important in other cancers. An integral part of the PI3K pathway, PIK3CA is an oncogene with two hotspots for activating mutations: the 542/545 region of the helical domain and the 1047 region of the kinase domain. The interaction of PIK3CA with the AKT and mTOR pathways is the subject of an immense amount of research and development, and PI3K inhibitors have exhibited some success in recent clinical trials. While PI3K monotherapies are likely insufficient, there is interest in pursuing PI3K inhibition in combination with other therapies including TKI's, MEK inhibitors, PARP inhibitors, and - in breast cancer - aromatase inhibitors.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human PIK3CA expressed in E. Coli.
抗原种属
Human
基因名称
PIK3CA
基因ID
5290
蛋白名称
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Uniprot ID
P42336
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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