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Anti-Phospho-Vinculin (Tyr822) Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 Phospho-Vinculin (Tyr822)。Anti-Phospho-Vinculin (Tyr822) Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。
Anti-Phospho-Vinculin (Tyr822) Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 Phospho-Vinculin (Tyr822)。Anti-Phospho-Vinculin (Tyr822) Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-Phospho-Vinculin (Tyr822) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-Vinculin (Tyr822). Anti-Phospho-Vinculin (Tyr822) Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 交叉反应 | Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. |
| 组织特异性 | Metavinculin is muscle-specific. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008] |
| 免疫原 | KLH conjugated synthesised phosphopeptide: human Vinculin around the phosphorylation site of Tyr822 |
| 抗原种属 | Human |
| 基因名称 | VCL |
| 基因ID | |
| 蛋白名称 | Vinculin |
| Uniprot ID | |
| 功能 | Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion. |
| 分子量 | Theoretical: 124 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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