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Anti-Phospho-Vinculin (Tyr822) Polyclonal Antibody 2

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产品编号 TMAB-11416

Anti-Phospho-Vinculin (Tyr822) Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 Phospho-Vinculin (Tyr822)。Anti-Phospho-Vinculin (Tyr822) Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

Anti-Phospho-Vinculin (Tyr822) Polyclonal Antibody 2

Anti-Phospho-Vinculin (Tyr822) Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
产品编号 TMAB-11416

Anti-Phospho-Vinculin (Tyr822) Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 Phospho-Vinculin (Tyr822)。Anti-Phospho-Vinculin (Tyr822) Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

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50 μL
¥ 1,165
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100 μL
¥ 1,970
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200 μL
¥ 2,780
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产品介绍

生物活性
产品描述
Anti-Phospho-Vinculin (Tyr822) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-Vinculin (Tyr822). Anti-Phospho-Vinculin (Tyr822) Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
交叉反应
Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
组织特异性Metavinculin is muscle-specific.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthesised phosphopeptide: human Vinculin around the phosphorylation site of Tyr822
抗原种属
Human
基因名称
VCL
基因ID
蛋白名称
Vinculin
Uniprot ID
功能
Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
化学信息
分子量Theoretical: 124 kDa.
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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