Anti-Phospho-TFII I (Tyr248) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TFII I (Tyr248). Anti-Phospho-TFII I (Tyr248) Polyclonal Antibody can be used in WB.

IgG

Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)

WB: 1:500-2000

Polyclonal

KLH conjugated synthesised phosphopeptide: human TFII I around the phosphorylation site of Tyr248

Human

GTF2I

General transcription factor II-I

Interacts with the basal transcription machinery by coordinating the formation of a multiprotein complex at the C-FOS promoter, and linking specific signal responsive activator complexes. Promotes the formation of stable high-order complexes of SRF and PHOX1 and interacts cooperatively with PHOX1 to promote serum-inducible transcription of a reporter gene deriven by the C-FOS serum response element (SRE). Acts as a coregulator for USF1 by binding independently two promoter elements, a pyrimidine-rich initiator (Inr) and an upstream E-box. Required for the formation of functional ARID3A DNA-binding complexes and for activation of immunoglobulin heavy-chain transcription upon B-lymphocyte activation.