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Anti-Phospho-Tau (Thr231) Antibody (4Q665) 是一种 Mouse 抗体,靶向 Phospho-Tau (Thr231)。Anti-Phospho-Tau (Thr231) Antibody (4Q665) 可用于 WB。
Anti-Phospho-Tau (Thr231) Antibody (4Q665) 是一种 Mouse 抗体,靶向 Phospho-Tau (Thr231)。Anti-Phospho-Tau (Thr231) Antibody (4Q665) 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 200 μg | ¥ 5,580 | 5日内发货 | |
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-Phospho-Tau (Thr231) Antibody (4Q665) is a Mouse antibody targeting Phospho-Tau (Thr231). Anti-Phospho-Tau (Thr231) Antibody (4Q665) can be used in WB. |
| Ig Type | IgG |
| 克隆号 | 4Q665 |
| 反应种属 | Human |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 亚细胞定位 | Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Note=Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components. |
| 组织特异性 | Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system. |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M PBS (pH7.4). |
| 研究背景 | Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system. |
| 免疫原 | KLH conjugated synthetic peptide: human phospho-Tau (Thr231) |
| 抗原种属 | Human |
| 基因名称 | MAPT |
| 基因ID | |
| 蛋白名称 | Microtubule-associated protein tau |
| Uniprot ID | |
| 功能 | Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. |
| 分子量 | Theoretical: 46/79 kDa. |
| 运输方式 | Shipping with blue ice. |