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Anti-Phospho-SPHK2 (Thr614) Polyclonal Antibody 2

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产品编号 TMAB-11314

Anti-Phospho-SPHK2 (Thr614) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-SPHK2 (Thr614)。Anti-Phospho-SPHK2 (Thr614) Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Phospho-SPHK2 (Thr614) Polyclonal Antibody 2

Anti-Phospho-SPHK2 (Thr614) Polyclonal Antibody 2

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Rating icon 还可以
产品编号 TMAB-11314

Anti-Phospho-SPHK2 (Thr614) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-SPHK2 (Thr614)。Anti-Phospho-SPHK2 (Thr614) Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
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100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-SPHK2 (Thr614) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-SPHK2 (Thr614). Anti-Phospho-SPHK2 (Thr614) Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
交叉反应
Mouse,Rat (predicted:Human,Dog,Pig,Cow,Horse,Sheep)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Isoform 1: Cytoplasm. Membrane. Isoform 2: Lysosome membrane.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a kinase that phosphorylates sphingosine into sphingosine-1-phosphate, which is involved in cell differentiation, motility, and apoptosis. The encoded protein plays a role in maintaining cellular levels of sphingosine-1-phosphate. The gene product also enhances apoptosis in different cell types and suppresses cellular proliferation. In mast cells, the encoded protein is necessary for influx of calcium, protein kinase C activation, and cytokine production and degranulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
抗原信息
免疫原
KLH conjugated synthesised phosphopeptide: human SPHK2 around the phosphorylation site of Thr614
抗原种属
Human
基因名称
SPHK2
基因ID
56848
蛋白名称
Sphingosine kinase 2
Uniprot ID
Q9NRA0
功能
Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra-and extracellular functions. Also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine. Binds phosphoinositides.
化学信息
分子量Theoretical: 72 kDa.
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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