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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-RCC1 (Ser11) Polyclonal Antibody 2

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货号 TMAB-11234

Anti-Phospho-RCC1 (Ser11) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-RCC1 (Ser11)。Anti-Phospho-RCC1 (Ser11) Polyclonal Antibody 2 可用于 WB。

Anti-Phospho-RCC1 (Ser11) Polyclonal Antibody 2

Anti-Phospho-RCC1 (Ser11) Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-11234

Anti-Phospho-RCC1 (Ser11) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-RCC1 (Ser11)。Anti-Phospho-RCC1 (Ser11) Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-RCC1 (Ser11) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-RCC1 (Ser11). Anti-Phospho-RCC1 (Ser11) Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Note=Becomes dispersed throughout the cytoplasm during mitosis.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Ran GTPase plays important roles in nucleocytoplasmic transport in interphase and in both spindle formation and nuclear envelope (NE) assembly during mitosis. The latter functions rely on the presence of high local concentrations of GTP bound Ran near mitotic chromatin. RanGTP localization has been proposed to result from the association of Ran's GDP/GTP exchange factor, RCC1, with chromatin , but Ran is shown here to bind directly to chromatin in two modes, either dependent or independent of RCC1, and, where bound, to increase the affinity of chromatin for NE membranes.
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human RCC1 around the phosphorylation site of Ser11
抗原种属
Human
基因名称
RCC1
基因ID
1104
蛋白名称
Regulator of chromosome condensation
Uniprot ID
P18754
功能
Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.
化学信息
分子量Theoretical: 45 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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