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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-PLCG1 (Tyr775) Polyclonal Antibody

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货号 TMAB-11172

Anti-Phospho-PLCG1 (Tyr775) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-PLCG1 (Tyr775)。Anti-Phospho-PLCG1 (Tyr775) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Phospho-PLCG1 (Tyr775) Polyclonal Antibody

Anti-Phospho-PLCG1 (Tyr775) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-11172

Anti-Phospho-PLCG1 (Tyr775) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-PLCG1 (Tyr775)。Anti-Phospho-PLCG1 (Tyr775) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-PLCG1 (Tyr775) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PLCG1 (Tyr775). Anti-Phospho-PLCG1 (Tyr775) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog,Cow,Horse)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell projection, lamellipodium. Cell projection, ruffle. Note=Rapidly redistributed to ruffles and lamellipodia structures in response to epidermal growth factor (EGF) treatment.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human PLC gamma 1 around the phosphorylation site of Tyr775
抗原种属
Human
基因名称
PLCG1
基因ID
5335
蛋白名称
1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase gamma-1
Uniprot ID
P19174
功能
Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.
化学信息
分子量Theoretical: 148 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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