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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-PKC gamma (Thr514) Polyclonal Antibody

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货号 TMAB-11155

Anti-Phospho-PKC gamma (Thr514) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-PKC gamma (Thr514)。Anti-Phospho-PKC gamma (Thr514) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Phospho-PKC gamma (Thr514) Polyclonal Antibody

Anti-Phospho-PKC gamma (Thr514) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-11155

Anti-Phospho-PKC gamma (Thr514) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-PKC gamma (Thr514)。Anti-Phospho-PKC gamma (Thr514) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-PKC gamma (Thr514) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PKC gamma (Thr514). Anti-Phospho-PKC gamma (Thr514) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Pig,Cow,Horse,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.Cell membrane.
组织特异性Expressed in Purkinje cells of the cerebellar cortex.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human PKC gamma around the phosphorylation site of Thr514
抗原种属
Human
基因名称
PRKCG
基因ID
5582
蛋白名称
Protein kinase C gamma type
Uniprot ID
P05129
功能
This is a calcium-activated, phospholipid-dependent, serine- and threonine-specific enzyme.
PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
化学信息
分子量Theoretical: 78 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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