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Anti-Phospho-PKA alpha+beta (Thr198) Polyclonal Antibody

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货号 TMAB-11144

Anti-Phospho-PKA alpha+beta (Thr198) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-PKA alpha+beta (Thr198)。Anti-Phospho-PKA alpha+beta (Thr198) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Phospho-PKA alpha+beta (Thr198) Polyclonal Antibody

Anti-Phospho-PKA alpha+beta (Thr198) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-11144

Anti-Phospho-PKA alpha+beta (Thr198) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-PKA alpha+beta (Thr198)。Anti-Phospho-PKA alpha+beta (Thr198) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
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100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-Phospho-PKA alpha+beta (Thr198) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PKA alpha+beta (Thr198). Anti-Phospho-PKA alpha+beta (Thr198) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Cell membrane. Nucleus. Note=Translocates into the nucleus (monomeric catalytic subunit). The inactive holoenzyme is found in the cytoplasm.
组织特异性Isoform 1 is most abundant in the brain, with low level expression in kidney. Isoform 2 is predominantly expressed in thymus, spleen and kidney. Isoform 3 and isoform 4 are only expressed in the brain.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Several alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jun 2011].
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human PRKACB around the phosphorylation site of Thr198
抗原种属
Human
基因名称
PRKACB
基因ID
蛋白名称
cAMP-dependent protein kinase catalytic subunit beta
功能
Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.
化学信息
分子量Theoretical: 40 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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