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Anti-Phospho-HDAC8 (Ser39) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-HDAC8 (Ser39)。Anti-Phospho-HDAC8 (Ser39) Polyclonal Antibody 可用于 IHC,IF。
Anti-Phospho-HDAC8 (Ser39) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-HDAC8 (Ser39)。Anti-Phospho-HDAC8 (Ser39) Polyclonal Antibody 可用于 IHC,IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,495 | 5日内发货 | |
100 μL | ¥ 2,235 | 5日内发货 |
产品描述 | Anti-Phospho-HDAC8 (Ser39) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HDAC8 (Ser39). Anti-Phospho-HDAC8 (Ser39) Polyclonal Antibody can be used in IHC,IF. |
别名 | p-HDAC8 (Ser39), p-HDAC8 (S39), HDAC8 (p-Ser39), HDAC8 (p-S39) |
Ig Type | IgG |
交叉反应 | Human |
验证活性 | 1. Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using HDAC8 (Phospho-Ser39) Antibody TMAC-01791 (left) or the same antibody preincubated with blocking peptide (right). 2. Immunofluorescence staining of methanol-fixed Hela cells using HDAC8 (Phospho-Ser39) Antibody TMAC-01791. |
应用 | |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC8 gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of serine 39 (R-A-S(p)-M-V) derived from Human HDAC8 |
抗原种属 | human |
Uniprot ID |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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