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Anti-Phospho-Caspase-8 (Ser347) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Caspase-8 (Ser347)。Anti-Phospho-Caspase-8 (Ser347) Polyclonal Antibody 可用于 WB,IHC-P,IF(paraffin section),ELISA。
Anti-Phospho-Caspase-8 (Ser347) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Caspase-8 (Ser347)。Anti-Phospho-Caspase-8 (Ser347) Polyclonal Antibody 可用于 WB,IHC-P,IF(paraffin section),ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,230 | 5日内发货 |
产品描述 | Anti-Phospho-Caspase-8 (Ser347) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Caspase-8 (Ser347). Anti-Phospho-Caspase-8 (Ser347) Polyclonal Antibody can be used in WB,IHC-P,IF(paraffin section),ELISA. |
别名 | p-Caspase-8 (Ser347), p-Caspase-8 (S347), Caspase-8 (p-Ser347), Caspase-8 (p-S347) |
Ig Type | IgG |
交叉反应 | Human,Rat |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-300; ELISA: 1:5000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
性状 | Liquid |
缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
研究背景 | caspase 8(CASP8) Homo sapiens This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases. Many alt |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | A synthesized phosphopeptide: human Caspase 8 around the phosphorylation site of Ser347. AA range:313-362 |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 55 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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