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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-PAX5 Monoclonal Antibody (1T561)

Synonyms: BSAP
货号 TMAT-1205 一键复制产品信息
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Anti-PAX5 Monoclonal Antibody (1T561) 是一种 Mouse 抗体，靶向 PAX5。Anti-PAX5 Monoclonal Antibody (1T561) 可用于 IHC。

Anti-PAX5 Monoclonal Antibody (1T561)

一键复制产品信息
Rating icon 还可以
货号 TMAT-1205

别名 BSAP

Anti-PAX5 Monoclonal Antibody (1T561) 是一种 Mouse 抗体，靶向 PAX5。Anti-PAX5 Monoclonal Antibody (1T561) 可用于 IHC。

Anti-PAX5 Monoclonal Antibody (1T561)
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产品介绍

生物活性
产品描述
Anti-PAX5 Monoclonal Antibody (1T561) is a Mouse antibody targeting PAX5. Anti-PAX5 Monoclonal Antibody (1T561) can be used in IHC.
别名
BSAP
Ig Type
IgG1
克隆号
1T561
反应种属
Human
应用IHC
推荐剂量
IHC: 1/200-1/1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternatively spliced transcript variants encoding different isoforms have been described but their biological validity has not been determined.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human PAX5 (AA: 235-382) expressed in E. Coli.
抗原种属
Human
基因名称
PAX5
基因ID
5079
蛋白名称
Paired box protein Pax-5
Uniprot ID
Q02548
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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