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Anti-PAR4 Monoclonal Antibody (8Z790) 是一种 Mouse 抗体,靶向 PAR4。Anti-PAR4 Monoclonal Antibody (8Z790) 可用于 IHC。
别名 PAWR
Anti-PAR4 Monoclonal Antibody (8Z790) 是一种 Mouse 抗体,靶向 PAR4。Anti-PAR4 Monoclonal Antibody (8Z790) 可用于 IHC。

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| 产品描述 | Anti-PAR4 Monoclonal Antibody (8Z790) is a Mouse antibody targeting PAR4. Anti-PAR4 Monoclonal Antibody (8Z790) can be used in IHC. |
| 别名 | PAWR |
| Ig Type | IgG1 |
| 克隆号 | 8Z790 |
| 反应种属 | Human |
| 应用 | IHC |
| 推荐剂量 | IHC: 1/200-1/1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | Ascitic fluid containing 0.03% sodium azide. |
| 浓度 | 1 mg/mL |
| 研究背景 | Prostate apoptosis response 4 (Par4) is a 38kD protein originally identified as the product of a gene that is upregulated in prostate tumor cells undergoing apoptosis. It is a leucine zipper and death domain containing protein whose levels increase in neurons undergoing apoptosis as a result of trophic factor withdrawal or exposure to oxidative and metabolic insults. Par4 levels are reported to be increased in their lumbar spinal cord specimens further suggesting a role in neuronal degeneration. The tumor suppressor WT1 represses and activates transcription. The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms tumor. Par4 is a WT1 interacting protein that also functions as a transcriptional repressor. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of PAR4(aa1-330) expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | PAWR |
| 基因ID | |
| 蛋白名称 | PRKC apoptosis WT1 regulator protein |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |