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Anti-P16 Monoclonal Antibody (4W326)

Synonyms: TP16, P19ARF, P19, P16-INK4A, P16INK4A, P16INK4, P14ARF, P14, MTS-1, MTS1, MLM, INK4A, INK4, CMM2, CDKN2A, CDKN2, CDK4I, CAI2, ARF
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Anti-P16 Monoclonal Antibody (4W326) 是一种 Mouse 抗体,靶向 P16。Anti-P16 Monoclonal Antibody (4W326) 可用于 IHC。

Anti-P16 Monoclonal Antibody (4W326)

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货号 TMAT-1038

别名 TP16, P19ARF, P19, P16-INK4A, P16INK4A, P16INK4, P14ARF, P14, MTS-1, MTS1, MLM, INK4A, INK4, CMM2, CDKN2A, CDKN2, CDK4I, CAI2, ARF

Anti-P16 Monoclonal Antibody (4W326) 是一种 Mouse 抗体,靶向 P16。Anti-P16 Monoclonal Antibody (4W326) 可用于 IHC。

Anti-P16 Monoclonal Antibody (4W326)
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产品介绍


生物活性
产品描述
Anti-P16 Monoclonal Antibody (4W326) is a Mouse antibody targeting P16. Anti-P16 Monoclonal Antibody (4W326) can be used in IHC.
别名
TP16, P19ARF, P19, P16-INK4A, P16INK4A, P16INK4, P14ARF, P14, MTS-1, MTS1, MLM, INK4A, INK4, CMM2, CDKN2A, CDKN2, CDK4I, CAI2, ARF
Ig Type
IgG1
克隆号
4W326
反应种属
Human
应用IHC
推荐剂量
IHC: 1/200-1/1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液Ascitic fluid containing 0.03% sodium azide.
浓度1 mg/mL
研究背景p16 (cyclin-dependent kinase inhibitor 2A, INK4a) is a tumor suppressor protein. It is a specific inhibitor of Cdk 4 / Cdk 6, and a tumor suppressor involved in the pathogenesis of a variety of malignancies. Recent analyses of the p16 INK4a gene revealed homozygous deletions, nonsense, missense, or frameshift mutations in several human cancers. Although the frequency of p16 INK4a abnormalities is higher in tumor derived cell lines than in unselected primary tumors, significant subsets of clinical cases with aberrant p16 INK4a gene have been reported among melanomas, gliomas, esophageal, pancreatic, lung, and urinary bladder carcinomas, and some types of leukemia.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of P16 expressed in E. Coli.
抗原种属
Human
基因名称
CDKN2A
基因ID
蛋白名称
Cyclin-dependent kinase inhibitor 2A
Uniprot ID
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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