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Anti-P16 Monoclonal Antibody (4W326) 是一种 Mouse 抗体,靶向 P16。Anti-P16 Monoclonal Antibody (4W326) 可用于 IHC。
别名 TP16, P19ARF, P19, P16-INK4A, P16INK4A, P16INK4, P14ARF, P14, MTS-1, MTS1, MLM, INK4A, INK4, CMM2, CDKN2A, CDKN2, CDK4I, CAI2, ARF
Anti-P16 Monoclonal Antibody (4W326) 是一种 Mouse 抗体,靶向 P16。Anti-P16 Monoclonal Antibody (4W326) 可用于 IHC。

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| 产品描述 | Anti-P16 Monoclonal Antibody (4W326) is a Mouse antibody targeting P16. Anti-P16 Monoclonal Antibody (4W326) can be used in IHC. |
| 别名 | TP16, P19ARF, P19, P16-INK4A, P16INK4A, P16INK4, P14ARF, P14, MTS-1, MTS1, MLM, INK4A, INK4, CMM2, CDKN2A, CDKN2, CDK4I, CAI2, ARF |
| Ig Type | IgG1 |
| 克隆号 | 4W326 |
| 反应种属 | Human |
| 应用 | IHC |
| 推荐剂量 | IHC: 1/200-1/1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | Ascitic fluid containing 0.03% sodium azide. |
| 浓度 | 1 mg/mL |
| 研究背景 | p16 (cyclin-dependent kinase inhibitor 2A, INK4a) is a tumor suppressor protein. It is a specific inhibitor of Cdk 4 / Cdk 6, and a tumor suppressor involved in the pathogenesis of a variety of malignancies. Recent analyses of the p16 INK4a gene revealed homozygous deletions, nonsense, missense, or frameshift mutations in several human cancers. Although the frequency of p16 INK4a abnormalities is higher in tumor derived cell lines than in unselected primary tumors, significant subsets of clinical cases with aberrant p16 INK4a gene have been reported among melanomas, gliomas, esophageal, pancreatic, lung, and urinary bladder carcinomas, and some types of leukemia. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of P16 expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | CDKN2A |
| 基因ID | |
| 蛋白名称 | Cyclin-dependent kinase inhibitor 2A |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |