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Anti-NUP98 Monoclonal Antibody (5H871)

Synonyms: Nup98-96, NUP96, NUP196, ADIR2
货号 TMAT-1114 一键复制产品信息
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Anti-NUP98 Monoclonal Antibody (5H871) 是一种 Mouse 抗体,靶向 NUP98。Anti-NUP98 Monoclonal Antibody (5H871) 可用于 WB,FCM。

Anti-NUP98 Monoclonal Antibody (5H871)

一键复制产品信息
Rating icon 还可以
货号 TMAT-1114

别名 Nup98-96, NUP96, NUP196, ADIR2

Anti-NUP98 Monoclonal Antibody (5H871) 是一种 Mouse 抗体,靶向 NUP98。Anti-NUP98 Monoclonal Antibody (5H871) 可用于 WB,FCM。

Anti-NUP98 Monoclonal Antibody (5H871)
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产品介绍


生物活性
产品描述
Anti-NUP98 Monoclonal Antibody (5H871) is a Mouse antibody targeting NUP98. Anti-NUP98 Monoclonal Antibody (5H871) can be used in WB,FCM.
别名
Nup98-96, NUP96, NUP196, ADIR2
Ig Type
IgG1
克隆号
5H871
反应种属
Human,Monkey
应用WBFCM
推荐剂量
WB: 1/500-1/2000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景Nuclear pore complexes (NPCs) regulate the transport of macromolecules between the nucleus and cytoplasm, and are composed of many polypeptide subunits, many of which belong to the nucleoporin family. This gene belongs to the nucleoporin gene family and encodes a 186 kDa precursor protein that undergoes autoproteolytic cleavage to generate a 98 kDa nucleoporin and 96 kDa nucleoporin. The 98 kDa nucleoporin contains a Gly-Leu-Phe-Gly (GLGF) repeat domain and participates in many cellular processes, including nuclear import, nuclear export, mitotic progression, and regulation of gene expression. The 96 kDa nucleoporin is a scaffold component of the NPC. Proteolytic cleavage is important for targeting of the proteins to the NPC. Translocations between this gene and many other partner genes have been observed in different leukemias. Rearrangements typically result in chimeras with the N-terminal GLGF domain of this gene to the C-terminus of the partner gene. Alternative splicing results in multiple transcript variants encoding different isoforms, at least two of which are proteolytically processed. Some variants lack the region that encodes the 96 kDa nucleoporin.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human NUP98 (AA: 1-218) expressed in E. Coli.
抗原种属
Human
基因名称
NUP98
基因ID
蛋白名称
Nuclear pore complex protein Nup98-Nup96
Uniprot ID
化学信息
分子量Theoretical: 197.5 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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