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Anti-NUP98 Monoclonal Antibody (5H871) 是一种 Mouse 抗体,靶向 NUP98。Anti-NUP98 Monoclonal Antibody (5H871) 可用于 WB,FCM。
别名 Nup98-96, NUP96, NUP196, ADIR2
Anti-NUP98 Monoclonal Antibody (5H871) 是一种 Mouse 抗体,靶向 NUP98。Anti-NUP98 Monoclonal Antibody (5H871) 可用于 WB,FCM。

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| 产品描述 | Anti-NUP98 Monoclonal Antibody (5H871) is a Mouse antibody targeting NUP98. Anti-NUP98 Monoclonal Antibody (5H871) can be used in WB,FCM. |
| 别名 | Nup98-96, NUP96, NUP196, ADIR2 |
| Ig Type | IgG1 |
| 克隆号 | 5H871 |
| 反应种属 | Human,Monkey |
| 应用 | WBFCM |
| 推荐剂量 | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/mL |
| 研究背景 | Nuclear pore complexes (NPCs) regulate the transport of macromolecules between the nucleus and cytoplasm, and are composed of many polypeptide subunits, many of which belong to the nucleoporin family. This gene belongs to the nucleoporin gene family and encodes a 186 kDa precursor protein that undergoes autoproteolytic cleavage to generate a 98 kDa nucleoporin and 96 kDa nucleoporin. The 98 kDa nucleoporin contains a Gly-Leu-Phe-Gly (GLGF) repeat domain and participates in many cellular processes, including nuclear import, nuclear export, mitotic progression, and regulation of gene expression. The 96 kDa nucleoporin is a scaffold component of the NPC. Proteolytic cleavage is important for targeting of the proteins to the NPC. Translocations between this gene and many other partner genes have been observed in different leukemias. Rearrangements typically result in chimeras with the N-terminal GLGF domain of this gene to the C-terminus of the partner gene. Alternative splicing results in multiple transcript variants encoding different isoforms, at least two of which are proteolytically processed. Some variants lack the region that encodes the 96 kDa nucleoporin. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human NUP98 (AA: 1-218) expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | NUP98 |
| 基因ID | |
| 蛋白名称 | Nuclear pore complex protein Nup98-Nup96 |
| Uniprot ID |
| 分子量 | Theoretical: 197.5 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |