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Anti-MUC16 Monoclonal Antibody (4M881)

Synonyms: CA125
货号 TMAT-1445 一键复制产品信息
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Anti-MUC16 Monoclonal Antibody (4M881) 是一种 Mouse 抗体,靶向 MUC16。Anti-MUC16 Monoclonal Antibody (4M881) 可用于 IHC,FCM。

Anti-MUC16 Monoclonal Antibody (4M881)

一键复制产品信息
Rating icon 还可以
货号 TMAT-1445

别名 CA125

Anti-MUC16 Monoclonal Antibody (4M881) 是一种 Mouse 抗体,靶向 MUC16。Anti-MUC16 Monoclonal Antibody (4M881) 可用于 IHC,FCM。

Anti-MUC16 Monoclonal Antibody (4M881)
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产品介绍


生物活性
产品描述
Anti-MUC16 Monoclonal Antibody (4M881) is a Mouse antibody targeting MUC16. Anti-MUC16 Monoclonal Antibody (4M881) can be used in IHC,FCM.
别名
CA125
Ig Type
IgG1
克隆号
4M881
反应种属
Human
应用IHCFCM
推荐剂量
IHC: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景This gene encodes a protein that is a member of the mucin family. Mucins are high molecular weight, O-glycosylated proteins that play an important role in forming a protective mucous barrier, and are found on the apical surfaces of the epithelia. The encoded protein is a membrane-tethered mucin that contains an extracellular domain at its amino terminus, a large tandem repeat domain, and a transmembrane domain with a short cytoplasmic domain. The amino terminus is highly glycosylated, while the repeat region contains 156 amino acid repeats unit that are rich in serines, threonines, and prolines. Interspersed within the repeats are Sea urchin sperm protein Enterokinase and Agrin (SEA) modules, leucine-rich repeats and ankyrin (ANK) repeats. These regions together form the ectodomain, and there is a potential cleavage site found near an SEA module close to the transmembrane domain. This protein is thought to play a role in forming a barrier, protecting epithelial cells from pathogens. Products of this gene have been used as a marker for different cancers, with higher expression levels associated with poorer outcomes.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human MUC16 (AA: extra 1-200) expressed in E. Coli.
抗原种属
Human
基因名称
MUC16
基因ID
蛋白名称
Mucin-16
Uniprot ID
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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