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Anti-MUC16 Monoclonal Antibody (4M881) 是一种 Mouse 抗体,靶向 MUC16。Anti-MUC16 Monoclonal Antibody (4M881) 可用于 IHC,FCM。
别名 CA125
Anti-MUC16 Monoclonal Antibody (4M881) 是一种 Mouse 抗体,靶向 MUC16。Anti-MUC16 Monoclonal Antibody (4M881) 可用于 IHC,FCM。

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| 产品描述 | Anti-MUC16 Monoclonal Antibody (4M881) is a Mouse antibody targeting MUC16. Anti-MUC16 Monoclonal Antibody (4M881) can be used in IHC,FCM. |
| 别名 | CA125 |
| Ig Type | IgG1 |
| 克隆号 | 4M881 |
| 反应种属 | Human |
| 应用 | IHCFCM |
| 推荐剂量 | IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/mL |
| 研究背景 | This gene encodes a protein that is a member of the mucin family. Mucins are high molecular weight, O-glycosylated proteins that play an important role in forming a protective mucous barrier, and are found on the apical surfaces of the epithelia. The encoded protein is a membrane-tethered mucin that contains an extracellular domain at its amino terminus, a large tandem repeat domain, and a transmembrane domain with a short cytoplasmic domain. The amino terminus is highly glycosylated, while the repeat region contains 156 amino acid repeats unit that are rich in serines, threonines, and prolines. Interspersed within the repeats are Sea urchin sperm protein Enterokinase and Agrin (SEA) modules, leucine-rich repeats and ankyrin (ANK) repeats. These regions together form the ectodomain, and there is a potential cleavage site found near an SEA module close to the transmembrane domain. This protein is thought to play a role in forming a barrier, protecting epithelial cells from pathogens. Products of this gene have been used as a marker for different cancers, with higher expression levels associated with poorer outcomes. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human MUC16 (AA: extra 1-200) expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | MUC16 |
| 基因ID | |
| 蛋白名称 | Mucin-16 |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |