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Anti-MLL Monoclonal Antibody (3B204)

Synonyms: MLL
货号 TMAT-1209 一键复制产品信息
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Anti-MLL Monoclonal Antibody (3B204) 是一种 Mouse 抗体,靶向 MLL。Anti-MLL Monoclonal Antibody (3B204) 可用于 IHC。

Anti-MLL Monoclonal Antibody (3B204)

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货号 TMAT-1209

别名 MLL

Anti-MLL Monoclonal Antibody (3B204) 是一种 Mouse 抗体,靶向 MLL。Anti-MLL Monoclonal Antibody (3B204) 可用于 IHC。

Anti-MLL Monoclonal Antibody (3B204)
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产品介绍


生物活性
产品描述
Anti-MLL Monoclonal Antibody (3B204) is a Mouse antibody targeting MLL. Anti-MLL Monoclonal Antibody (3B204) can be used in IHC.
别名
MLL
Ig Type
IgG1
克隆号
3B204
反应种属
Human
应用IHC
推荐剂量
IHC: 1/200-1/1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide.
浓度1 mg/mL
研究背景Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila). Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA. This is a multistep process, called the transcription cycle,that includes five stages: preinitiation, promoter, clearance, elongation and termination. Elongation is thought to be a critical stage for the regulation of gene expression. ELL (11-19 lysine-rich leukemia protein, also designated MEN) functions as an RNA polymerase II elongation factor that increases the rateof transcription by suppressing transient pausing by RNA polymerase II. Also, ELL is thought to regulate cellular proliferation. ELL is abundantly expressed in peripheral blood leukocytes, skeletal muscle, placenta and testis, and has lower expression in spleen, thymus, heart, brain, lung, kidney, liver and ovary.The gene encoding human ELL, which maps to chromosome 19p13.1, is one of several genes which undergo translocation with the MLL gene on chromo-some 11q23 in acute myeloid leukemia. MLL (myeloid/lymphoid leukemia,also designated ALL-1 and HRX) is a 430 kDa protein that regulates embryonal and hematopoietic development.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of MLL (aa3751-3968) expressed in E. Coli.
抗原种属
Human
基因名称
KMT2A
基因ID
蛋白名称
Histone-lysine N-methyltransferase 2A
Uniprot ID
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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