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Anti-MLL Monoclonal Antibody (3B204) 是一种 Mouse 抗体,靶向 MLL。Anti-MLL Monoclonal Antibody (3B204) 可用于 IHC。
别名 MLL
Anti-MLL Monoclonal Antibody (3B204) 是一种 Mouse 抗体,靶向 MLL。Anti-MLL Monoclonal Antibody (3B204) 可用于 IHC。

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| 产品描述 | Anti-MLL Monoclonal Antibody (3B204) is a Mouse antibody targeting MLL. Anti-MLL Monoclonal Antibody (3B204) can be used in IHC. |
| 别名 | MLL |
| Ig Type | IgG1 |
| 克隆号 | 3B204 |
| 反应种属 | Human |
| 应用 | IHC |
| 推荐剂量 | IHC: 1/200-1/1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide. |
| 浓度 | 1 mg/mL |
| 研究背景 | Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila). Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA. This is a multistep process, called the transcription cycle,that includes five stages: preinitiation, promoter, clearance, elongation and termination. Elongation is thought to be a critical stage for the regulation of gene expression. ELL (11-19 lysine-rich leukemia protein, also designated MEN) functions as an RNA polymerase II elongation factor that increases the rateof transcription by suppressing transient pausing by RNA polymerase II. Also, ELL is thought to regulate cellular proliferation. ELL is abundantly expressed in peripheral blood leukocytes, skeletal muscle, placenta and testis, and has lower expression in spleen, thymus, heart, brain, lung, kidney, liver and ovary.The gene encoding human ELL, which maps to chromosome 19p13.1, is one of several genes which undergo translocation with the MLL gene on chromo-some 11q23 in acute myeloid leukemia. MLL (myeloid/lymphoid leukemia,also designated ALL-1 and HRX) is a 430 kDa protein that regulates embryonal and hematopoietic development. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of MLL (aa3751-3968) expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | KMT2A |
| 基因ID | |
| 蛋白名称 | Histone-lysine N-methyltransferase 2A |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |