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Anti-MECP2 Monoclonal Antibody (4N330) 是一种 Mouse 抗体,靶向 MECP2。Anti-MECP2 Monoclonal Antibody (4N330) 可用于 WB,IHC,IF,FCM。
别名 RTT, RTS, RS, PPMX, MRXSL, MRXS13, MRX79, MRX16, AUTSX3
Anti-MECP2 Monoclonal Antibody (4N330) 是一种 Mouse 抗体,靶向 MECP2。Anti-MECP2 Monoclonal Antibody (4N330) 可用于 WB,IHC,IF,FCM。

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| 产品描述 | Anti-MECP2 Monoclonal Antibody (4N330) is a Mouse antibody targeting MECP2. Anti-MECP2 Monoclonal Antibody (4N330) can be used in WB,IHC,IF,FCM. |
| 别名 | RTT, RTS, RS, PPMX, MRXSL, MRXS13, MRX79, MRX16, AUTSX3 |
| Ig Type | IgG1 |
| 克隆号 | 4N330 |
| 反应种属 | Human |
| 应用 | WBIHCIFFCM |
| 推荐剂量 | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/mL |
| 研究背景 | DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human MECP2 (AA: 7-148) expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | MECP2 |
| 基因ID | |
| 蛋白名称 | Methyl-CpG-binding protein 2 |
| Uniprot ID |
| 分子量 | Theoretical: 52.4 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |