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顶部产品介绍偶联与修饰抗原信息化学信息储存和溶解信息计算器

Anti-MCL1 Monoclonal Antibody (5E149)

Synonyms: TM, MCL1S, MCL1L, MCL1-ES, mcl1/EAT, Mcl-1, EAT, bcl2-L-3, BCL2L3
货号 TMAT-1239 一键复制产品信息
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Anti-MCL1 Monoclonal Antibody (5E149) 是一种 Mouse 抗体，靶向 MCL1。Anti-MCL1 Monoclonal Antibody (5E149) 可用于 WB,IHC,IF。

Anti-MCL1 Monoclonal Antibody (5E149)

一键复制产品信息
Rating icon 还可以
货号 TMAT-1239

别名 TM, MCL1S, MCL1L, MCL1-ES, mcl1/EAT, Mcl-1, EAT, bcl2-L-3, BCL2L3

Anti-MCL1 Monoclonal Antibody (5E149) 是一种 Mouse 抗体，靶向 MCL1。Anti-MCL1 Monoclonal Antibody (5E149) 可用于 WB,IHC,IF。

Anti-MCL1 Monoclonal Antibody (5E149)
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产品介绍

生物活性
产品描述
Anti-MCL1 Monoclonal Antibody (5E149) is a Mouse antibody targeting MCL1. Anti-MCL1 Monoclonal Antibody (5E149) can be used in WB,IHC,IF.
别名
TM, MCL1S, MCL1L, MCL1-ES, mcl1/EAT, Mcl-1, EAT, bcl2-L-3, BCL2L3
Ig Type
IgG1
克隆号
5E149
反应种属
Human
应用WBIHCIF
推荐剂量
WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景Mcl-1 (Myeloid cell leukemia-1) is Bcl-2-related and was identified as an early-induction gene thatincreased in expression during the differentiation of human myeloblastic leukemia cell ML-1, or exposure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lymphocytes undergoing apoptosis following treatment with apoptotic stimuli such as TGF-alpha 1 and forskolin. Expression of Mcl-1 is able to delay apoptosis induced by over-expression of c-myc in CHO 5AHSmyc cells. In hematopoietic FDC-P1 cells, Mcl-1 interacts with another Bcl-2-related protein, Bax, and prolongs cell viability after treatment with different apoptotic reagents.This monoclonal antibody detected a 37kd MCL1 in BCBL-1 cell lysate.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human MCL-1 expressed in E. Coli.
抗原种属
Human
基因名称
MCL1
基因ID
4170
蛋白名称
Induced myeloid leukemia cell differentiation protein Mcl-1
Uniprot ID
Q07820
化学信息
分子量Theoretical: 37 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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