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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-MAP3K5 Monoclonal Antibody (4H549)

Synonyms: MEKK5, MAPKKK5, ASK1
货号 TMAT-1507 一键复制产品信息
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Anti-MAP3K5 Monoclonal Antibody (4H549) 是一种 Mouse 抗体，靶向 MAP3K5。Anti-MAP3K5 Monoclonal Antibody (4H549) 可用于 IHC,IF,FCM。

Anti-MAP3K5 Monoclonal Antibody (4H549)

一键复制产品信息
Rating icon 还可以
货号 TMAT-1507

别名 MEKK5, MAPKKK5, ASK1

Anti-MAP3K5 Monoclonal Antibody (4H549) 是一种 Mouse 抗体，靶向 MAP3K5。Anti-MAP3K5 Monoclonal Antibody (4H549) 可用于 IHC,IF,FCM。

Anti-MAP3K5 Monoclonal Antibody (4H549)
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产品介绍

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产品描述
Anti-MAP3K5 Monoclonal Antibody (4H549) is a Mouse antibody targeting MAP3K5. Anti-MAP3K5 Monoclonal Antibody (4H549) can be used in IHC,IF,FCM.
别名
MEKK5, MAPKKK5, ASK1
Ig Type
IgG1
克隆号
4H549
反应种属
Human
应用IHCIFFCM
推荐剂量
IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide.
浓度1 mg/mL
研究背景Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human MAP3K5 expressed in E. Coli.
抗原种属
Human
基因名称
MAP3K5
基因ID
4217
蛋白名称
Mitogen-activated protein kinase kinase kinase 5
Uniprot ID
Q99683
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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