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Anti-MAP2K3 Monoclonal Antibody (8H965) 是一种 Mouse 抗体,靶向 MAP2K3。Anti-MAP2K3 Monoclonal Antibody (8H965) 可用于 IHC,IF,FCM。
别名 SAPKK-2, SAPKK2, PRKMK3, MKK3, MEK3, MAPKK3
Anti-MAP2K3 Monoclonal Antibody (8H965) 是一种 Mouse 抗体,靶向 MAP2K3。Anti-MAP2K3 Monoclonal Antibody (8H965) 可用于 IHC,IF,FCM。

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| 产品描述 | Anti-MAP2K3 Monoclonal Antibody (8H965) is a Mouse antibody targeting MAP2K3. Anti-MAP2K3 Monoclonal Antibody (8H965) can be used in IHC,IF,FCM. |
| 别名 | SAPKK-2, SAPKK2, PRKMK3, MKK3, MEK3, MAPKK3 |
| Ig Type | IgG1 |
| 克隆号 | 8H965 |
| 反应种属 | Human |
| 应用 | IHCIFFCM |
| 推荐剂量 | IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/mL |
| 研究背景 | The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human MAP2K3 (AA: 1-138) expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | MAP2K3 |
| 基因ID | |
| 蛋白名称 | Dual specificity mitogen-activated protein kinase kinase 3 |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |