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Anti-MAP2K2 Monoclonal Antibody (8E150) 是一种 Mouse 抗体,靶向 MAP2K2。Anti-MAP2K2 Monoclonal Antibody (8E150) 可用于 WB,IF,FCM。
别名 MKK2, MEK2, MAPKK2
Anti-MAP2K2 Monoclonal Antibody (8E150) 是一种 Mouse 抗体,靶向 MAP2K2。Anti-MAP2K2 Monoclonal Antibody (8E150) 可用于 WB,IF,FCM。

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| 产品描述 | Anti-MAP2K2 Monoclonal Antibody (8E150) is a Mouse antibody targeting MAP2K2. Anti-MAP2K2 Monoclonal Antibody (8E150) can be used in WB,IF,FCM. |
| 别名 | MKK2, MEK2, MAPKK2 |
| Ig Type | IgG1 |
| 克隆号 | 8E150 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WBIFFCM |
| 推荐剂量 | WB: 1/500-1/2000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide. |
| 浓度 | 1 mg/mL |
| 研究背景 | MAP2K2, also called MEK2, it is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human MAP2K2 expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | MAP2K2 |
| 基因ID | |
| 蛋白名称 | Dual specificity mitogen-activated protein kinase kinase 2 |
| Uniprot ID |
| 分子量 | Theoretical: 44 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |