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Anti-LYN Monoclonal Antibody (4S766) 是一种 Mouse 抗体,靶向 LYN。Anti-LYN Monoclonal Antibody (4S766) 可用于 WB。
别名 JTK8, FLJ26625
Anti-LYN Monoclonal Antibody (4S766) 是一种 Mouse 抗体,靶向 LYN。Anti-LYN Monoclonal Antibody (4S766) 可用于 WB。

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| 产品描述 | Anti-LYN Monoclonal Antibody (4S766) is a Mouse antibody targeting LYN. Anti-LYN Monoclonal Antibody (4S766) can be used in WB. |
| 别名 | JTK8, FLJ26625 |
| Ig Type | IgG2b |
| 克隆号 | 4S766 |
| 反应种属 | Human |
| 应用 | WB |
| 推荐剂量 | WB: 1/500-1/2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide. |
| 浓度 | 1 mg/mL |
| 研究背景 | Lyn (also known as p53/56 Lyn) is a membrane-associated protein tyrosine kinase (PTK) mostly expressed in hemopoietic cells which is important in cellular signaling. It contains an SH2 and SH3 domain and has been found to be cleaved after activation of caspases in apoptosis. A member of the Src family of PTKs, there are two known isoforms for Lyn which plays an indispensable role in the Fc epsilon RI (Fcer1) and the B-cell IgM receptor signaling pathway and is essential for Syk activation and Lat phosphorylation after Fcer1 aggregation and can also phosphor-ylate Tec on multiple residues. Lyn can also be regulated by IL-2 and IL-3.Lyn is a member of the src family of non-receptor protein tyrosine kinases that is predominantly expressed in haematopoietic tissues. Like all members of the src family, lyn is thought to participate in signal transduction from cell surface receptors that lack intrinsic tyrosine kinase activity. It is associated with a number of cell surface receptors including the B cell antigen receptor and immunoglobulin E receptor (FceRI). |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of LYN expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | LYN |
| 基因ID | |
| 蛋白名称 | Tyrosine-protein kinase Lyn |
| Uniprot ID |
| 分子量 | Theoretical: 56 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |