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Anti-LMNA Monoclonal Antibody (5B815) 是一种 Mouse 抗体,靶向 LMNA。Anti-LMNA Monoclonal Antibody (5B815) 可用于 WB,IHC。
别名 PRO1, LMNL1, LMNC, LMN1, LFP, LDP1, IDC, HGPS, FPLD2, FPLD, FPL, EMD2, CMT2B1, CMD1A, CDDC, CDCD1
Anti-LMNA Monoclonal Antibody (5B815) 是一种 Mouse 抗体,靶向 LMNA。Anti-LMNA Monoclonal Antibody (5B815) 可用于 WB,IHC。

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| 产品描述 | Anti-LMNA Monoclonal Antibody (5B815) is a Mouse antibody targeting LMNA. Anti-LMNA Monoclonal Antibody (5B815) can be used in WB,IHC. |
| 别名 | PRO1, LMNL1, LMNC, LMN1, LFP, LDP1, IDC, HGPS, FPLD2, FPLD, FPL, EMD2, CMT2B1, CMD1A, CDDC, CDCD1 |
| Ig Type | IgG1 |
| 克隆号 | 5B815 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WBIHC |
| 推荐剂量 | WB: 1/500-1/2000; IHC: 1/200-1/1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | Ascitic fluid containing 0.03% sodium azide. |
| 浓度 | 1 mg/mL |
| 研究背景 | The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encodes three type A lamin isoforms. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human LMNA expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | LMNA |
| 基因ID | |
| 蛋白名称 | Prelamin-A/C |
| Uniprot ID |
| 分子量 | Theoretical: 74 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |