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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-LAMB1 Monoclonal Antibody (6U331)

Synonyms: MGC142015, CLM
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Anti-LAMB1 Monoclonal Antibody (6U331) 是一种 Mouse 抗体，靶向 LAMB1。Anti-LAMB1 Monoclonal Antibody (6U331) 可用于 IHC。

Anti-LAMB1 Monoclonal Antibody (6U331)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0742

别名 MGC142015, CLM

Anti-LAMB1 Monoclonal Antibody (6U331) 是一种 Mouse 抗体，靶向 LAMB1。Anti-LAMB1 Monoclonal Antibody (6U331) 可用于 IHC。

Anti-LAMB1 Monoclonal Antibody (6U331)
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产品介绍

生物活性
产品描述
Anti-LAMB1 Monoclonal Antibody (6U331) is a Mouse antibody targeting LAMB1. Anti-LAMB1 Monoclonal Antibody (6U331) can be used in IHC.
别名
MGC142015, CLM
Ig Type
IgG2a
克隆号
6U331
反应种属
Human
应用IHC
推荐剂量
IHC: 1/200-1/1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide.
浓度1 mg/mL
研究背景LAMB1: laminin, beta 1. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the beta chain isoform laminin, beta 1. The beta 1 chain has 7 structurally distinct domains which it shares with other beta chain isomers. The C-terminal helical region containing domains I and II are separated by domain alpha, domains III and V contain several EGF-like repeats, and domains IV and VI have a globular conformation. Laminin, beta 1 is expressed in most tissues that produce basement membranes, and is one of the 3 chains constituting laminin 1, the first laminin isolated from Engelbreth-Holm-Swarm (EHS) tumor. A sequence in the beta 1 chain that is involved in cell attachment, chemotaxis, and binding to the laminin receptor was identified and shown to have the capacity to inhibit metastasis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of LAMB1 (aa31-270) expressed in E. Coli.
抗原种属
Human
基因名称
LAMB1
基因ID
3912
蛋白名称
Laminin subunit beta-1
Uniprot ID
P07942
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
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