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Anti-KMT2A Monoclonal Antibody (8N714) 是一种 Mouse 抗体,靶向 KMT2A。Anti-KMT2A Monoclonal Antibody (8N714) 可用于 IHC,IF,FCM。
别名 WDSTS, TRX1, MLL1A, MLL1, MLL, HTRX1, HRX, CXXC7, ALL-1
Anti-KMT2A Monoclonal Antibody (8N714) 是一种 Mouse 抗体,靶向 KMT2A。Anti-KMT2A Monoclonal Antibody (8N714) 可用于 IHC,IF,FCM。

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| 产品描述 | Anti-KMT2A Monoclonal Antibody (8N714) is a Mouse antibody targeting KMT2A. Anti-KMT2A Monoclonal Antibody (8N714) can be used in IHC,IF,FCM. |
| 别名 | WDSTS, TRX1, MLL1A, MLL1, MLL, HTRX1, HRX, CXXC7, ALL-1 |
| Ig Type | IgG1 |
| 克隆号 | 8N714 |
| 反应种属 | Human |
| 应用 | IHCIFFCM |
| 推荐剂量 | IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/mL |
| 研究背景 | This gene encodes a transcriptional coactivator that plays an essential role in regulating gene expression during early development and hematopoiesis. The encoded protein contains multiple conserved functional domains. One of these domains, the SET domain, is responsible for its histone H3 lysine 4 (H3K4) methyltransferase activity which mediates chromatin modifications associated with epigenetic transcriptional activation. This protein is processed by the enzyme Taspase 1 into two fragments, MLL-C and MLL-N. These fragments reassociate and further assemble into different multiprotein complexes that regulate the transcription of specific target genes, including many of the HOX genes. Multiple chromosomal translocations involving this gene are the cause of certain acute lymphoid leukemias and acute myeloid leukemias. Alternate splicing results in multiple transcript variants. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human KMT2A (AA:150-400) expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | KMT2A |
| 基因ID | |
| 蛋白名称 | Histone-lysine N-methyltransferase 2A |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |