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顶部产品介绍偶联与修饰抗原信息化学信息储存和溶解信息计算器

Anti-KIR3DL1 Monoclonal Antibody (4R593)

Synonyms: NKB1B, NKB1, NKAT-3, NKAT3, KIR3DL1/S1, KIR, CD158E1
货号 TMAT-1051 一键复制产品信息
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Anti-KIR3DL1 Monoclonal Antibody (4R593) 是一种 Mouse 抗体，靶向 KIR3DL1。Anti-KIR3DL1 Monoclonal Antibody (4R593) 可用于 WB,FCM。

Anti-KIR3DL1 Monoclonal Antibody (4R593)

一键复制产品信息
Rating icon 还可以
货号 TMAT-1051

别名 NKB1B, NKB1, NKAT-3, NKAT3, KIR3DL1/S1, KIR, CD158E1

Anti-KIR3DL1 Monoclonal Antibody (4R593) 是一种 Mouse 抗体，靶向 KIR3DL1。Anti-KIR3DL1 Monoclonal Antibody (4R593) 可用于 WB,FCM。

Anti-KIR3DL1 Monoclonal Antibody (4R593)
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产品介绍

生物活性
产品描述
Anti-KIR3DL1 Monoclonal Antibody (4R593) is a Mouse antibody targeting KIR3DL1. Anti-KIR3DL1 Monoclonal Antibody (4R593) can be used in WB,FCM.
别名
NKB1B, NKB1, NKAT-3, NKAT3, KIR3DL1/S1, KIR, CD158E1
Ig Type
IgG2b
克隆号
4R593
反应种属
Human,Rat
应用WBFCM
推荐剂量
WB: 1/500-1/2000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human KIR3DL1 (AA: extra 22-340) expressed in HEK293 cells.
抗原种属
Human
基因名称
KIR3DL1
基因ID
3811
蛋白名称
Killer cell immunoglobulin-like receptor 3DL1
Uniprot ID
P43629
化学信息
分子量Theoretical: 49 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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