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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-IGF1R-Beta Monoclonal Antibody (8J90)

Synonyms: IGF1R
货号 TMAT-0748 一键复制产品信息
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Anti-IGF1R-Beta Monoclonal Antibody (8J90) 是一种 Mouse 抗体，靶向 IGF1R-Beta。Anti-IGF1R-Beta Monoclonal Antibody (8J90) 可用于 IHC。

Anti-IGF1R-Beta Monoclonal Antibody (8J90)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0748

别名 IGF1R

Anti-IGF1R-Beta Monoclonal Antibody (8J90) 是一种 Mouse 抗体，靶向 IGF1R-Beta。Anti-IGF1R-Beta Monoclonal Antibody (8J90) 可用于 IHC。

Anti-IGF1R-Beta Monoclonal Antibody (8J90)
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产品介绍

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产品描述
Anti-IGF1R-Beta Monoclonal Antibody (8J90) is a Mouse antibody targeting IGF1R-Beta. Anti-IGF1R-Beta Monoclonal Antibody (8J90) can be used in IHC.
别名
IGF1R
Ig Type
IgG2a
克隆号
8J90
反应种属
Human
应用IHC
推荐剂量
IHC: 1/200-1/1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液Ascitic fluid containing 0.03% sodium azide.
浓度1 mg/mL
研究背景IGF1R(insulin-like growth factor 1 receptor), a transmembrane receptor tyrosine kinase, is widely expressed in many cell types within fetal and postnatal tissues, and in many cell lines. Upon binding to its ligands, IGF-I and IGF-II, receptor autophosphorylation occurs. The triple tyrosine cluster within the kinase domain (Tyr1131, Tyr1135 and Tyr1136) is the earliest major site of autophosphorylation. Phosphorylation of these three tyrosine residues is necessary for kinase activation.Insulin receptors (IRs) share significant similarity with IGF1 receptors in both structure and function,including an equivalent triple tyrosine cluster within the activation loop of the kinase domain (Tyr1146, Tyr1150 and Tyr1151).Tyrosine autophosphorylation of insulin receptor is one of the earliest cellular responses to insulin stimulation. Autophosphorylation begins with phosphorylation of Tyr1146 and either Tyr1150 or Tyr1151. Full kinase activation requires the triple tyrosine phosphorylation.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of IGF1R-Beta (AA: 1101-1367) expressed in E. Coli.
抗原种属
Human
基因名称
IGF1R
基因ID
3480
蛋白名称
Insulin-like growth factor 1 receptor
Uniprot ID
P08069
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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