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Anti-human CD8 Antibody (2D51) 是一种 Mouse 抗体,靶向 human CD8。Anti-human CD8 Antibody (2D51) 可用于 FCM。
Anti-human CD8 Antibody (2D51) 是一种 Mouse 抗体,靶向 human CD8。Anti-human CD8 Antibody (2D51) 可用于 FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μg | ¥ 1,865 | 5日内发货 |
| 产品描述 | Anti-human CD8 Antibody (2D51) is a Mouse antibody targeting human CD8. Anti-human CD8 Antibody (2D51) can be used in FCM. |
| Ig Type | Mouse IgG1, k |
| 克隆号 | 2D51 |
| 反应种属 | Human |
| 应用 | FCM |
| 推荐剂量 | FCM: 1μg/Test |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织特异性 | Most prominently found in the gastrointestinal tract, skin, lung, and brain but not in liver. |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Protein G purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4). |
| 浓度 | 1mg/ml |
| 研究背景 | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020] |
| 免疫原 | Recombinant Protein: human CD8 |
| 抗原种属 | Human |
| 基因名称 | CD8A |
| 基因ID | |
| 蛋白名称 | T-cell surface glycoprotein CD8 alpha chain |
| Uniprot ID | |
| 功能 | Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains. |
| 分子量 | Theoretical: 27 kDa. Actual: 32-34 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |