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Anti-HNRNPU Monoclonal Antibody (1R870) 是一种 Mouse 抗体,靶向 HNRNPU。Anti-HNRNPU Monoclonal Antibody (1R870) 可用于 WB,IHC,FCM。
别名 U21.1, SAF-A, HNRPU, hnRNP U
Anti-HNRNPU Monoclonal Antibody (1R870) 是一种 Mouse 抗体,靶向 HNRNPU。Anti-HNRNPU Monoclonal Antibody (1R870) 可用于 WB,IHC,FCM。

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| 产品描述 | Anti-HNRNPU Monoclonal Antibody (1R870) is a Mouse antibody targeting HNRNPU. Anti-HNRNPU Monoclonal Antibody (1R870) can be used in WB,IHC,FCM. |
| 别名 | U21.1, SAF-A, HNRPU, hnRNP U |
| Ig Type | IgG1 |
| 克隆号 | 1R870 |
| 反应种属 | Human |
| 应用 | WBIHCFCM |
| 推荐剂量 | WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide. |
| 浓度 | 1 mg/mL |
| 研究背景 | This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they form complexes with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene contains a RNA binding domain and scaffold-associated region (SAR)-specific bipartite DNA-binding domain. This protein is also thought to be involved in the packaging of hnRNA into large ribonucleoprotein complexes. During apoptosis, this protein is cleaved in a caspase-dependent way. Cleavage occurs at the SALD site, resulting in a loss of DNA-binding activity and a concomitant detachment of this protein from nuclear structural sites. But this cleavage does not affect the function of the encoded protein in RNA metabolism. At least two alternatively spliced transcript variants have been identified for this gene. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human HNRNPU expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | HNRNPU |
| 基因ID | |
| 蛋白名称 | Heterogeneous nuclear ribonucleoprotein U |
| Uniprot ID |
| 分子量 | Theoretical: 90 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |