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Anti-HNRNPU Monoclonal Antibody (1R870)

Synonyms: U21.1, SAF-A, HNRPU, hnRNP U
货号 TMAT-1185 一键复制产品信息
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Anti-HNRNPU Monoclonal Antibody (1R870) 是一种 Mouse 抗体,靶向 HNRNPU。Anti-HNRNPU Monoclonal Antibody (1R870) 可用于 WB,IHC,FCM。

Anti-HNRNPU Monoclonal Antibody (1R870)

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Rating icon 还可以
货号 TMAT-1185

别名 U21.1, SAF-A, HNRPU, hnRNP U

Anti-HNRNPU Monoclonal Antibody (1R870) 是一种 Mouse 抗体,靶向 HNRNPU。Anti-HNRNPU Monoclonal Antibody (1R870) 可用于 WB,IHC,FCM。

Anti-HNRNPU Monoclonal Antibody (1R870)
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产品介绍


生物活性
产品描述
Anti-HNRNPU Monoclonal Antibody (1R870) is a Mouse antibody targeting HNRNPU. Anti-HNRNPU Monoclonal Antibody (1R870) can be used in WB,IHC,FCM.
别名
U21.1, SAF-A, HNRPU, hnRNP U
Ig Type
IgG1
克隆号
1R870
反应种属
Human
应用WBIHCFCM
推荐剂量
WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide.
浓度1 mg/mL
研究背景This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they form complexes with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene contains a RNA binding domain and scaffold-associated region (SAR)-specific bipartite DNA-binding domain. This protein is also thought to be involved in the packaging of hnRNA into large ribonucleoprotein complexes. During apoptosis, this protein is cleaved in a caspase-dependent way. Cleavage occurs at the SALD site, resulting in a loss of DNA-binding activity and a concomitant detachment of this protein from nuclear structural sites. But this cleavage does not affect the function of the encoded protein in RNA metabolism. At least two alternatively spliced transcript variants have been identified for this gene.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human HNRNPU expressed in E. Coli.
抗原种属
Human
基因名称
HNRNPU
基因ID
蛋白名称
Heterogeneous nuclear ribonucleoprotein U
Uniprot ID
化学信息
分子量Theoretical: 90 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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