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顶部产品介绍偶联与修饰抗原信息化学信息储存和溶解信息计算器

Anti-HLA-DRB1 Monoclonal Antibody (3O58)

Synonyms: SS1, HLA-DRB, HLA-DR1B, DRB1
货号 TMAT-0649 一键复制产品信息
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Anti-HLA-DRB1 Monoclonal Antibody (3O58) 是一种 Mouse 抗体，靶向 HLA-DRB1。Anti-HLA-DRB1 Monoclonal Antibody (3O58) 可用于 WB,IHC,FCM。

Anti-HLA-DRB1 Monoclonal Antibody (3O58)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0649

别名 SS1, HLA-DRB, HLA-DR1B, DRB1

Anti-HLA-DRB1 Monoclonal Antibody (3O58) 是一种 Mouse 抗体，靶向 HLA-DRB1。Anti-HLA-DRB1 Monoclonal Antibody (3O58) 可用于 WB,IHC,FCM。

Anti-HLA-DRB1 Monoclonal Antibody (3O58)
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产品介绍

生物活性
产品描述
Anti-HLA-DRB1 Monoclonal Antibody (3O58) is a Mouse antibody targeting HLA-DRB1. Anti-HLA-DRB1 Monoclonal Antibody (3O58) can be used in WB,IHC,FCM.
别名
SS1, HLA-DRB, HLA-DR1B, DRB1
Ig Type
IgG1
克隆号
3O58
反应种属
Human
应用WBIHCFCM
推荐剂量
WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells. The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Exon one encodes the leader peptide; exons 2 and 3 encode the two extracellular domains; exon 4 encodes the transmembrane domain; and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and some alleles have increased frequencies associated with certain diseases or conditions. For example, DRB1*1302 has been related to acute and chronic hepatitis B virus persistence. There are multiple pseudogenes of this gene.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human HLA-DRB1 (AA: 30-266) expressed in E. Coli.
抗原种属
Human
基因名称
HLA-DRB1
基因ID
3123
蛋白名称
HLA class II histocompatibility antigen, DRB1 beta chain
Uniprot ID
P01911
化学信息
分子量Theoretical: 29.9 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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