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Anti-HIF1A Monoclonal Antibody (6E576) 是一种 Mouse 抗体,靶向 HIF1A。Anti-HIF1A Monoclonal Antibody (6E576) 可用于 WB,IHC,IF。
别名 PASD8, MOP1, HIF1-ALPHA, HIF-1alpha, HIF1A, HIF1, bHLHe78
Anti-HIF1A Monoclonal Antibody (6E576) 是一种 Mouse 抗体,靶向 HIF1A。Anti-HIF1A Monoclonal Antibody (6E576) 可用于 WB,IHC,IF。

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| 产品描述 | Anti-HIF1A Monoclonal Antibody (6E576) is a Mouse antibody targeting HIF1A. Anti-HIF1A Monoclonal Antibody (6E576) can be used in WB,IHC,IF. |
| 别名 | PASD8, MOP1, HIF1-ALPHA, HIF-1alpha, HIF1A, HIF1, bHLHe78 |
| Ig Type | IgG1 |
| 克隆号 | 6E576 |
| 反应种属 | Human,Mouse,Monkey |
| 应用 | WBIHCIF |
| 推荐剂量 | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide. |
| 浓度 | 1 mg/mL |
| 研究背景 | Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified. (provided by RefSeq) Tissue specificity: Expressed in most tissues with highest levels in kidney and heart. Overexpressed in the majority of common human cancers and their metastases, due to the presence of intratumoral hypoxia and as a result of mutations in genes encoding oncoproteins and tumor suppressors. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human HIF1A expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | HIF1A |
| 基因ID | |
| 蛋白名称 | Hypoxia-inducible factor 1-alpha |
| Uniprot ID |
| 分子量 | Theoretical: 120 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |