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Anti-GSK3A Monoclonal Antibody (6L466) 是一种 Mouse 抗体,靶向 GSK3A。Anti-GSK3A Monoclonal Antibody (6L466) 可用于 WB,IF。
别名 GSK3 alpha, DKFZp686D0638
Anti-GSK3A Monoclonal Antibody (6L466) 是一种 Mouse 抗体,靶向 GSK3A。Anti-GSK3A Monoclonal Antibody (6L466) 可用于 WB,IF。

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| 产品描述 | Anti-GSK3A Monoclonal Antibody (6L466) is a Mouse antibody targeting GSK3A. Anti-GSK3A Monoclonal Antibody (6L466) can be used in WB,IF. |
| 别名 | GSK3 alpha, DKFZp686D0638 |
| Ig Type | IgG1 |
| 克隆号 | 6L466 |
| 反应种属 | Human |
| 应用 | WBIF |
| 推荐剂量 | WB: 1/500-1/2000; IF: 1/200-1/1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | Ascitic fluid containing 0.03% sodium azide. |
| 浓度 | 1 mg/mL |
| 研究背景 | Glycogen synthase kinase 3 alpha belongs to the Ser/Thr family of protein kinases, Cdc2/cdkx subfamily; GSK3 subsubfamily. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, myb, and the transcription factor c jun. GSK3 phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK3 and subsequently inhibits GSK3 acutely leading to the stimulation of glycogen synthesis. GSK3 signaling is performed by two isoforms, GSK3 alpha and GSK3 beta. The two isoforms share 97% sequence similarity within their catalytic domains. GSK3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics and cell motility. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of GSK3 alpha expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | GSK3A |
| 基因ID | |
| 蛋白名称 | Glycogen synthase kinase-3 alpha |
| Uniprot ID |
| 分子量 | Theoretical: 51 kDa |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |