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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-GNAS Monoclonal Antibody (3P506)

Synonyms: POH, PHP1C, PHP1B, PHP1A, NESP, GSP, GSA, GPSA, GNAS1, C20orf45, AHO
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Anti-GNAS Monoclonal Antibody (3P506) 是一种 Mouse 抗体，靶向 GNAS。Anti-GNAS Monoclonal Antibody (3P506) 可用于 IHC,FCM。

Anti-GNAS Monoclonal Antibody (3P506)

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货号 TMAT-1166

别名 POH, PHP1C, PHP1B, PHP1A, NESP, GSP, GSA, GPSA, GNAS1, C20orf45, AHO

Anti-GNAS Monoclonal Antibody (3P506) 是一种 Mouse 抗体，靶向 GNAS。Anti-GNAS Monoclonal Antibody (3P506) 可用于 IHC,FCM。

Anti-GNAS Monoclonal Antibody (3P506)
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产品介绍

生物活性
产品描述
Anti-GNAS Monoclonal Antibody (3P506) is a Mouse antibody targeting GNAS. Anti-GNAS Monoclonal Antibody (3P506) can be used in IHC,FCM.
别名
POH, PHP1C, PHP1B, PHP1A, NESP, GSP, GSA, GPSA, GNAS1, C20orf45, AHO
Ig Type
IgG2a
克隆号
3P506
反应种属
Human
应用IHCFCM
推荐剂量
IHC: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors. [provided by RefSeq, Aug 2012]
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human GNAS (AA: 42-188) expressed in E. Coli.
抗原种属
Human
基因名称
GNAS
基因ID
2778
蛋白名称
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Uniprot ID
P63092
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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