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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-FLT3 Monoclonal Antibody (1E870)

Synonyms: STK1, FLK-2, FLK2, CD135
货号 TMAT-1003 一键复制产品信息
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Anti-FLT3 Monoclonal Antibody (1E870) 是一种 Mouse 抗体，靶向 FLT3。Anti-FLT3 Monoclonal Antibody (1E870) 可用于 IHC。

Anti-FLT3 Monoclonal Antibody (1E870)

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货号 TMAT-1003

别名 STK1, FLK-2, FLK2, CD135

Anti-FLT3 Monoclonal Antibody (1E870) 是一种 Mouse 抗体，靶向 FLT3。Anti-FLT3 Monoclonal Antibody (1E870) 可用于 IHC。

Anti-FLT3 Monoclonal Antibody (1E870)
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产品介绍

生物活性
产品描述
Anti-FLT3 Monoclonal Antibody (1E870) is a Mouse antibody targeting FLT3. Anti-FLT3 Monoclonal Antibody (1E870) can be used in IHC.
别名
STK1, FLK-2, FLK2, CD135
Ig Type
IgG1
克隆号
1E870
反应种属
Human
应用IHC
推荐剂量
IHC: 1/200-1/1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human FLT3 (AA: 930-991) expressed in E. Coli.
抗原种属
Human
基因名称
FLT3
基因ID
2322
蛋白名称
Receptor-type tyrosine-protein kinase FLT3
Uniprot ID
P36888
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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