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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Ficolin 2 Polyclonal Antibody

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货号 TMAB-06029

Anti-Ficolin 2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Ficolin 2。Anti-Ficolin 2 Polyclonal Antibody 可用于 WB。

Anti-Ficolin 2 Polyclonal Antibody

Anti-Ficolin 2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-06029

Anti-Ficolin 2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Ficolin 2。Anti-Ficolin 2 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Ficolin 2 Polyclonal Antibody is a Rabbit antibody targeting Ficolin 2. Anti-Ficolin 2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
组织特异性Expressed by the liver and secreted in plasma.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Ficolin B is the designation in mouse and rat of a protein also known as L-ficolin, ficolin-2, collagen/fibrinogen domain-containing protein 2, serum lectin p35, EBP-37 or hucolin. Ficolin B is a 313 amino acid member of the ficolin lectin family. It is a secreted innate immunity pattern recognition molecule expressed in liver and plasma that forms a disulfide-linked homopolymer. This extensive N-terminal disulfide bridge formation can lead to a functional dodecamer polypeptide. Ficolin B binds to DNA ligands expressed by late apoptotic and necrotic cells to increase attachment and engulfment. Variation in ficolin B concentrations amongst individuals is associated with polymorphisms in the promoter and structural portion of the FCN2 gene. In patients with Behçet's disease (BD), there exists a significant difference in allele frequency for FCN2 gene single nucleotide polymorphisms (SNPs) within the -557 and -64 promoter sites within HLA-B51 positive and HLA-B51 negative subgroups.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Ficolin 2/Ficolin B
抗原种属
Human
基因名称
FCN2
基因ID
2220
蛋白名称
Ficolin-2
Uniprot ID
Q15485
功能
May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region.
化学信息
分子量Theoretical: 31 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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