购物车
您的购物车当前为空
Anti-FES Monoclonal Antibody (5U959) 是一种 Mouse 抗体,靶向 FES。Anti-FES Monoclonal Antibody (5U959) 可用于 IHC。
别名 FPS
Anti-FES Monoclonal Antibody (5U959) 是一种 Mouse 抗体,靶向 FES。Anti-FES Monoclonal Antibody (5U959) 可用于 IHC。

TargetMol的所有产品仅用作科学研究或药证申报,不能被用于人体,我们不向个人提供产品和服务。请您遵守承诺用途,不得违反法律法规规定用于任何其他用途。
| 产品描述 | Anti-FES Monoclonal Antibody (5U959) is a Mouse antibody targeting FES. Anti-FES Monoclonal Antibody (5U959) can be used in IHC. |
| 别名 | FPS |
| Ig Type | IgG1 |
| 克隆号 | 5U959 |
| 反应种属 | Human |
| 应用 | IHC |
| 推荐剂量 | IHC: 1/200-1/1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | Ascitic fluid containing 0.03% sodium azide. |
| 浓度 | 1 mg/mL |
| 研究背景 | FES (feline sarcoma oncogene) and Fer are the only two members of a unique family of cytoplasmic protein tyrosine kinases. FES and Fer contain a central Src homology-2 (SH2) domain and a carboxy-terminal tyrosine kinase catalytic domain. They are structurally distinguished from other members of cytoplasmic protein tyrosine kinase subfamilies by the presence of amino-terminal Fer/CIP4 homology and coiled-coil domains. FES was originally identified as an oncogene from avian and feline retroviruses. Human c-Fes has been implicated in myeloid, vascular endothelial and neuronal cell differentiation. FES has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Mutations may activate the FES kinase and thereby contribute to cancer. However, recent data strongly suggests that the c-FES protein-tyrosine kinase is a tumor suppressor rather than a dominant oncogene in colorectal cancer. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of FES (AA:613-822)expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | FES |
| 基因ID | |
| 蛋白名称 | Tyrosine-protein kinase Fes/Fps |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |