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Anti-FES Monoclonal Antibody (5U959)

Synonyms: FPS
货号 TMAT-0732 一键复制产品信息
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Anti-FES Monoclonal Antibody (5U959) 是一种 Mouse 抗体,靶向 FES。Anti-FES Monoclonal Antibody (5U959) 可用于 IHC。

Anti-FES Monoclonal Antibody (5U959)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0732

别名 FPS

Anti-FES Monoclonal Antibody (5U959) 是一种 Mouse 抗体,靶向 FES。Anti-FES Monoclonal Antibody (5U959) 可用于 IHC。

Anti-FES Monoclonal Antibody (5U959)
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产品介绍


生物活性
产品描述
Anti-FES Monoclonal Antibody (5U959) is a Mouse antibody targeting FES. Anti-FES Monoclonal Antibody (5U959) can be used in IHC.
别名
FPS
Ig Type
IgG1
克隆号
5U959
反应种属
Human
应用IHC
推荐剂量
IHC: 1/200-1/1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液Ascitic fluid containing 0.03% sodium azide.
浓度1 mg/mL
研究背景FES (feline sarcoma oncogene) and Fer are the only two members of a unique family of cytoplasmic protein tyrosine kinases. FES and Fer contain a central Src homology-2 (SH2) domain and a carboxy-terminal tyrosine kinase catalytic domain. They are structurally distinguished from other members of cytoplasmic protein tyrosine kinase subfamilies by the presence of amino-terminal Fer/CIP4 homology and coiled-coil domains. FES was originally identified as an oncogene from avian and feline retroviruses. Human c-Fes has been implicated in myeloid, vascular endothelial and neuronal cell differentiation. FES has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Mutations may activate the FES kinase and thereby contribute to cancer. However, recent data strongly suggests that the c-FES protein-tyrosine kinase is a tumor suppressor rather than a dominant oncogene in colorectal cancer.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of FES (AA:613-822)expressed in E. Coli.
抗原种属
Human
基因名称
FES
基因ID
蛋白名称
Tyrosine-protein kinase Fes/Fps
Uniprot ID
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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