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Anti-FER Monoclonal Antibody (9C529) 是一种 Mouse 抗体,靶向 FER。Anti-FER Monoclonal Antibody (9C529) 可用于 WB,IHC,IF。
别名 TYK3, FER
Anti-FER Monoclonal Antibody (9C529) 是一种 Mouse 抗体,靶向 FER。Anti-FER Monoclonal Antibody (9C529) 可用于 WB,IHC,IF。

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| 产品描述 | Anti-FER Monoclonal Antibody (9C529) is a Mouse antibody targeting FER. Anti-FER Monoclonal Antibody (9C529) can be used in WB,IHC,IF. |
| 别名 | TYK3, FER |
| Ig Type | IgG1 |
| 克隆号 | 9C529 |
| 反应种属 | Human,Mouse |
| 应用 | WBIHCIF |
| 推荐剂量 | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | Ascitic fluid containing 0.03% sodium azide. |
| 浓度 | 1 mg/mL |
| 研究背景 | FER (fer tyrosine kinase) is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases, which shares a functional domain and is involved in signaling pathways through receptor tyrosine kinases (RTK) and cytokine receptors. The Fes /Fps family is distinct from c-Src, c-Abl and related nRTKs and was originally distinguished as a homolog to retroviral oncoproteins. In vivo, Fer kinase assembles into homotrimers via conserved coiled-coil domains. The N-terminal coiled-coil domains of Fer can autophosphorylate in trans, thereby regulating their cellular function through differential phosphorylation states. Growth factor exposure can induce tyrosine phosphorylation of Fer and recruitment of Fer to RTK complexes containing p85. It is expressed predominantly in mature hematopoietic cells of the granulocytic and monocytic lineage, and has been shown to be expressed in vascular endothelial cells. Fer is implicated in insulin signaling, cell-cell signaling, human prostatic proliferative diseases, and is involved in the regulation of G1 progression. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human FER expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | FER |
| 基因ID | |
| 蛋白名称 | Tyrosine-protein kinase Fer |
| Uniprot ID |
| 分子量 | Theoretical: 95 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |