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Anti-FCER1G Polyclonal Antibody

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货号 TMAB-05943

Anti-FCER1G Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FCER1G。Anti-FCER1G Polyclonal Antibody 可用于 WB。

Anti-FCER1G Polyclonal Antibody

Anti-FCER1G Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05943

Anti-FCER1G Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FCER1G。Anti-FCER1G Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-FCER1G Polyclonal Antibody is a Rabbit antibody targeting FCER1G. Anti-FCER1G Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景IgE Fc Receptor I binds to the Fc region of immunoglobulins epsilon chain with high affinity, and is responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators such as histamines, responsible for the manifestations of allergy. IgE Fc Receptor I also induces the secretion of important lymphokines, effectors of the hypersensitivity response. It is a tetramer of a heavily glycosylated alpha chain, a beta chain, and two disulfide linked gamma chains. The gamma chains from Fc epsilon RI are also subunits of other Fc receptors. The gamma subunit is thought to be functionally significant in allowing the IgE Fc receptor to reach the cell surface. The cytoplasmic domains of the beta and gamma subunits each contain a conserved consesus sequence, ITAM, (immunoreceptor tyrosine activation motif). Phosphorylation of a pair of conserved tyrosine residues within this motif is required for signal transduction in mast cells and other hemopoietic cell types.
抗原信息
免疫原
KLH conjugated synthetic peptide: human FCER1G
抗原种属
Human
基因名称
FCER1G
基因ID
蛋白名称
High affinity immunoglobulin epsilon receptor subunit gamma
Uniprot ID
功能
Associates with a variety of FcR alpha chains to form a functional signaling complex. Regulates several aspects of the immune response. The gamma subunit has a critical role in allowing the IgE Fc receptor to reach the cell surface.
化学信息
分子量Theoretical: 10 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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