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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-FBXW8 Polyclonal Antibody

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货号 TMAB-05939

Anti-FBXW8 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FBXW8。Anti-FBXW8 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-FBXW8 Polyclonal Antibody

Anti-FBXW8 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05939

Anti-FBXW8 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FBXW8。Anti-FBXW8 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-FBXW8 Polyclonal Antibody is a Rabbit antibody targeting FBXW8. Anti-FBXW8 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景FBXO29, also designated F-box/WD repeat-containing protein 8 (FBXW8), is a 598 amino acid protein that contains one 40 amino acid F-box region, making it a member of the F-box family. FBXO29 also contains five WD repeats. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. F-box proteins are members of a large family that regulates cell cycle, immune response, signaling cascades and developmental programs by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-å and ∫-catenin, for degradation by the proteasome after ubiquitination. Functioning as a component of the SCF complex, FBXO29 is thought to recognize and bind to select phosphorylated proteins, thereby promoting their ubiquitination and subsequent degradation. FBXO29 exists as two isoforms as a result of alternative splicing events.
抗原信息
免疫原
KLH conjugated synthetic peptide: human FBXW8/FBXO29
抗原种属
Human
基因名称
FBXW8
基因ID
26259
蛋白名称
F-box/WD repeat-containing protein 8
Uniprot ID
Q8N3Y1
功能
Substrate-recognition component of a SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
化学信息
分子量Theoretical: 67 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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