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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-FBXO21 Polyclonal Antibody

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货号 TMAB-05929

Anti-FBXO21 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FBXO21。Anti-FBXO21 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-FBXO21 Polyclonal Antibody

Anti-FBXO21 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05929

Anti-FBXO21 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FBXO21。Anti-FBXO21 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-FBXO21 Polyclonal Antibody is a Rabbit antibody targeting FBXO21. Anti-FBXO21 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Dog,Pig,Cow,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Has some glucocorticoid receptor-responsive activity.
抗原信息
免疫原
KLH conjugated synthetic peptide: human FBXO21
抗原种属
Human
基因名称
FBXO21
基因ID
23014
蛋白名称
F-box only protein 21
Uniprot ID
O94952
功能
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex (By similarity).
化学信息
分子量Theoretical: 72 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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