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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Fbx32 Polyclonal Antibody

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货号 TMAB-05916

Anti-Fbx32 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Fbx32。Anti-Fbx32 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

Anti-Fbx32 Polyclonal Antibody

Anti-Fbx32 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05916

Anti-Fbx32 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Fbx32。Anti-Fbx32 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Fbx32 Polyclonal Antibody is a Rabbit antibody targeting Fbx32. Anti-Fbx32 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Dog,Pig,Cow,Horse,Rabbit)
应用IHC-PIHC-FrIFFCM
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 0.2μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Note=Shuttles between Cytoplasm and the nucleus.
组织特异性Specifically expressed in cardiac and skeletal muscle.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Fbx32 is an E3 ubiquitin ligase that initiates ATP dependent ubiquitin-mediated proteolysis and promotes muscle atrophy. It is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. It is also thought to recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation during skeletal muscle atrophy. Fbx32 interacts with MyoD by ubiquitination via a sequence found in transcriptional coactivators and therefore may play an important role in the course of muscle differentiation by determining the abundance of MyoD.
抗原信息
免疫原
KLH conjugated synthetic peptide: human MAFbx
抗原种属
Human
基因名称
FBXO32
基因ID
114907
蛋白名称
F-box only protein 32
Uniprot ID
Q969P5
功能
Substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1.
化学信息
分子量Theoretical: 42 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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