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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Factor I heavy chain Polyclonal Antibody

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货号 TMAB-05787

Anti-Factor I heavy chain Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Factor I heavy chain。Anti-Factor I heavy chain Polyclonal Antibody 可用于 WB。

Anti-Factor I heavy chain Polyclonal Antibody

Anti-Factor I heavy chain Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05787

Anti-Factor I heavy chain Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Factor I heavy chain。Anti-Factor I heavy chain Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

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产品描述
Anti-Factor I heavy chain Polyclonal Antibody is a Rabbit antibody targeting Factor I heavy chain. Anti-Factor I heavy chain Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted; extracellular space.
组织特异性Plasma.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The complement pathway is an important host defense system that contributes to both innate and acquired immunity. There are three pathways of complement activation: the classical pathway, lectin pathway and alternative pathway. Complement protein Factor I is a key serine protease that modulates the complement cascade by regulating the levels of C3 convertases. It circulates in plasma as a heavily N-glycosylated heterodimer made up of two disulfide linked chains, each carrying three N-linked oligosaccharide chains that may have both structural and functional roles in the interactions with the natural substrate and the cofactor during catalysis. Factor I is a serine protease with a high degree of specificity for C3b and C4b. It requires protein cofactors for cleavage of these complement proteins; Factor H, CR1 or MCP are required for C3b cleavage, and C4bp or CR1 are required for C4b cleavage.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Complement factor I heavy chain
抗原种属
Human
基因名称
CFI
基因ID
3426
蛋白名称
Complement factor I
Uniprot ID
P05156
功能
Responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively.
Subcellular Location : Secreted; extracellular space.
化学信息
分子量Theoretical: 35/63 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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