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别名 PCSK9 Inhibitor, GTPL7343, epatha, AMG-145, AMG 145
Anti-Evolocumab Antibody (4D251) 是一种 Rabbit 抗体,靶向 Evolocumab。Anti-Evolocumab Antibody (4D251) 可用于 ELISA, Sandwich ELISA, Competitive ELISA。
Anti-Evolocumab Antibody (4D251) 是一种 Rabbit 抗体,靶向 Evolocumab。Anti-Evolocumab Antibody (4D251) 可用于 ELISA, Sandwich ELISA, Competitive ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 40 μg | ¥ 3,218 | 5日内发货 |
| 产品描述 | Anti-Evolocumab Antibody (4D251) is a Rabbit antibody targeting Evolocumab. Anti-Evolocumab Antibody (4D251) can be used in ELISA, Sandwich ELISA, Competitive ELISA. |
| 别名 | PCSK9 Inhibitor, GTPL7343, epatha, AMG-145, AMG 145 |
| Ig Type | IgG, κ |
| 克隆号 | 4D251 |
| 特异性 | Evolocumab |
| 应用 | ELISASandwich ELISACompetitive ELISA |
| 推荐剂量 | ELISA: 0.01-1 µg/ml; Sandwich ELISA: 0.5-2 μg/ml; Competitive ELISA: 1-10 μg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 纯化方式 | Protein A affinity column |
| 性状 | Lyophilized. Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/mL. |
| 缓冲液 | Lyophilized with PBS, pH 7.2, containing 0.02% sodium azide. |
| 研究背景 | Evolocumab, also known as Repatha, is a monoclonal antibody used to treat hyperlipidemia through immunotherapy. This fully human monoclonal antibody works by blocking the activity of PCSK9, a protein responsible for breaking down LDL receptors. By inhibiting PCSK9, Repatha enhances the liver's capacity to remove LDL-C, commonly referred to as "bad" cholesterol, from the bloodstream. Evolocumab is the second PCSK9 inhibitor on the market, first being alirocumab. |
| 偶联 | Unconjugated |
| 免疫原 | Evolocumab |
| 储存方式 | The lyophilized product store at -20°C or -80°C for 12 months. The reconstituted antibody can be stored at 2°C-8°C for 2-3 weeks or at -20°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | -20°C for 1 year |