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Anti-ETV4 Monoclonal Antibody (3A480)

Synonyms: PEA3, NIK, HGK
货号 TMAT-1042 一键复制产品信息
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Anti-ETV4 Monoclonal Antibody (3A480) 是一种 Mouse 抗体,靶向 ETV4。Anti-ETV4 Monoclonal Antibody (3A480) 可用于 FCM。

Anti-ETV4 Monoclonal Antibody (3A480)

一键复制产品信息
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货号 TMAT-1042

别名 PEA3, NIK, HGK

Anti-ETV4 Monoclonal Antibody (3A480) 是一种 Mouse 抗体,靶向 ETV4。Anti-ETV4 Monoclonal Antibody (3A480) 可用于 FCM。

Anti-ETV4 Monoclonal Antibody (3A480)
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产品介绍


生物活性
产品描述
Anti-ETV4 Monoclonal Antibody (3A480) is a Mouse antibody targeting ETV4. Anti-ETV4 Monoclonal Antibody (3A480) can be used in FCM.
别名
PEA3, NIK, HGK
Ig Type
IgG1
克隆号
3A480
反应种属
Human
应用FCM
推荐剂量
FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide.
浓度1 mg/mL
研究背景ETV4: ets variant gene 4 (E1A enhancer binding protein, E1AF), also known as PEA3. Several members of the Ets gene family are known to encode sequencespecific DNA binding proteins. These include mouse PU.1, mouse and human Ets-1, Drosophila E74, chicken and human Ets-2 and rat GABP-a. Each of these proteins recognizes similar motifs in DNA that share a centrally located 5'-GGAA-3' element. For instance, PEA3 binds the motif 5'-AGGAAG-3' (the PEA-3 motif), but does not bind to the sequence 5'-AGGAAC-3', recognized by PU.1, although PU.1 binds equally well to both sequences. It appears that all of the Ets proteins recognize the same central core sequence but that each protein interacts with unique sequences that flank this core. PEA3 is expressed at readily detectable levels in cells of epithelial and fibroblastic origin but is not expressed in hematopoietic cells. This is in contrast to other members of the Ets gene family, such as Ets-1, Ets-2 and Fli-1, each of which is expressed primarily in cells of hematopoietic origin.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human ETV4 (aa50-109) expressed in E. Coli.
抗原种属
Human
基因名称
ETV4
基因ID
蛋白名称
ETS translocation variant 4
Uniprot ID
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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