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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-ERBB3 Monoclonal Antibody (1T826)

Synonyms: LCCS2, HER3
货号 TMAT-0911 一键复制产品信息
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Anti-ERBB3 Monoclonal Antibody (1T826) 是一种 Mouse 抗体，靶向 ERBB3。Anti-ERBB3 Monoclonal Antibody (1T826) 可用于 IHC。

Anti-ERBB3 Monoclonal Antibody (1T826)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0911

别名 LCCS2, HER3

Anti-ERBB3 Monoclonal Antibody (1T826) 是一种 Mouse 抗体，靶向 ERBB3。Anti-ERBB3 Monoclonal Antibody (1T826) 可用于 IHC。

Anti-ERBB3 Monoclonal Antibody (1T826)
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产品介绍

生物活性
产品描述
Anti-ERBB3 Monoclonal Antibody (1T826) is a Mouse antibody targeting ERBB3. Anti-ERBB3 Monoclonal Antibody (1T826) can be used in IHC.
别名
LCCS2, HER3
Ig Type
IgG1
克隆号
1T826
反应种属
Human
应用IHC
推荐剂量
IHC: 1/200-1/1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液Ascitic fluid containing 0.03% sodium azide.
浓度1 mg/mL
研究背景ERBB3: v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian). This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of ERBB3 (aa1175-1275) expressed in E. Coli.
抗原种属
Human
基因名称
ERBB3
基因ID
2065
蛋白名称
Receptor tyrosine-protein kinase erbB-3
Uniprot ID
P21860
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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