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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-ELK1 Monoclonal Antibody (5G166)

Synonyms: ELK1
货号 TMAT-0889 一键复制产品信息
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Anti-ELK1 Monoclonal Antibody (5G166) 是一种 Mouse 抗体，靶向 ELK1。Anti-ELK1 Monoclonal Antibody (5G166) 可用于 IHC。

Anti-ELK1 Monoclonal Antibody (5G166)

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货号 TMAT-0889

别名 ELK1

Anti-ELK1 Monoclonal Antibody (5G166) 是一种 Mouse 抗体，靶向 ELK1。Anti-ELK1 Monoclonal Antibody (5G166) 可用于 IHC。

Anti-ELK1 Monoclonal Antibody (5G166)
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产品介绍

生物活性
产品描述
Anti-ELK1 Monoclonal Antibody (5G166) is a Mouse antibody targeting ELK1. Anti-ELK1 Monoclonal Antibody (5G166) can be used in IHC.
别名
ELK1
Ig Type
IgG1
克隆号
5G166
反应种属
Human
应用IHC
推荐剂量
IHC: 1/200-1/1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液Ascitic fluid containing 0.03% sodium azide.
浓度1 mg/mL
研究背景The transcription factor ELK1 is a family of member of ETS oncogene family and of the ternary complex factor (TCF) subfamily,which is located on chromosome Xp11.2 and stimulates transcription. binds to purine-rich DNA sequences. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. Elk1 is phosphorylated by MAP kinase pathways at a cluster of S/T motifs at its C terminus,It appears to be a direct target of activated MAP kinase. Biochemical studies indicate that Elk1 is a good substrate for MAP kinase, the kinetics of Elk1phosphorylation and activation correlate with MAP kinase activity, and interfering mutants of MAP kinase block Elk1 activation in vivo. More recent studies have shown that Elk1 is also a target of the Stress Activated Kinase SAPK/JNK. Phosphorylation of Elk1 has also been implicated in synaptic plasticity in the adult hippocampus.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of ELK1 expressed in E. Coli.
抗原种属
Human
基因名称
ELK1
基因ID
2002
蛋白名称
ETS domain-containing protein Elk-1
Uniprot ID
P19419
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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